The prognostic value of acute-on-chronic liver failure during the course of severe alcoholic hepatitis
T Sersté, A Cornillie, H Njimi, M Pavesi, V Arroyo… - Journal of …, 2018 - Elsevier
Background & Aims A better identification of factors predicting death is needed in alcoholic
hepatitis (AH). Acute-on-chronic liver failure (ACLF) occurs during the course of liver disease
and can be identified when AH is diagnosed (prevalent ACLF [pACLF]) or during follow-up
(incidental ACLF [iACLF]). This study analyzed the impact of ACLF on outcomes in AH and
the role of infection on the onset of ACLF and death. Methods Patients admitted from July
2006 to July 2015 suffering from biopsy-proven severe (s) AH with a Maddrey discriminant …
hepatitis (AH). Acute-on-chronic liver failure (ACLF) occurs during the course of liver disease
and can be identified when AH is diagnosed (prevalent ACLF [pACLF]) or during follow-up
(incidental ACLF [iACLF]). This study analyzed the impact of ACLF on outcomes in AH and
the role of infection on the onset of ACLF and death. Methods Patients admitted from July
2006 to July 2015 suffering from biopsy-proven severe (s) AH with a Maddrey discriminant …
